Saffron Extract Supplement for Improving Sleep Quality in Adults with Moderate Insomnia

Saffron Spice in a wooden bowl on table

Saffron Extract Supplement for Improving Sleep Quality in Adults with Moderate Insomnia

Written by Tabish Mehraj, PhD. In this study, among 150 completers, saffron extract led to a greater reduction in insomnia symptoms (AIS) compared to placebo (between-group adjusted mean difference β =− 0.95 [95 % CI: − 1.79, − 0.11], P < .05). Sleep quality (SQS) improved significantly after 3 weeks (30 mg vs placebo: β =0.82 [95 % CI: 0.22, 1.41], P =004; 20 mg vs placebo: β =1.02 [0.43, 1.62], P <.001). Perceived stress (PSS) was significantly reduced with 30 mg or 20 mg saffron extract compared to placebo (30 mg vs placebo: β =− 1.87 [95 % CI: − 3.23, − 0.] P =.01; 20 mg vs placebo: β =− 1.89 [95 % CI: − 3.22, − 0.52], P =04).

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bowl of ground turmeric

Curcumin Reduces Inflammation and Improves Antioxidant Status in Type 2 Diabetic Patients

Written by Tabish Mehraj, PhD. In this study, curcumin supplementation was associated with significant reductions in pro-inflammatory cytokines (p < 0.001), hs-CRP, and NLR (p < 0.05), and with improved antioxidant status, as evidenced by increased SOD, TAS, and GPx, along with reduced MDA levels (p < 0.001). Improvements in metabolic parameters were observed, including lower FPG (112.0 mg/dL vs. 134.5 mg/dL; p < 0.001), HbA1c (6.10% vs. 6.40%; p < 0.05), and HOMA-IR (4.88 vs. 6.71; p < 0.001).

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CBD-rich Cannabis sativa Oil for Knee Osteoarthritis

Written by Tabish Mehraj, PhD. Following the intervention (i.e., 60 days or the trial endpoint), both the placebo and cannabis groups showed comparable improvements in pain scores, with no statistically significant differences in pain intensity. The CBD-rich cannabis oil was well-tolerated, as no patient experienced any serious adverse events or clinically significant changes in serum biomarkers.

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spoon with oats

Tocotrienol-Enriched Oats Improve HDL Cholesterol and Metabolic Health in Adults with Metabolic Syndrome

Written by Alexa Heathorn, MS, CNS. Daily consumption of 60 g of tocotrienol-enriched oats for 12 weeks significantly increased HDL cholesterol while improving triglycerides, fasting blood glucose, blood pressure, body composition, and metabolic syndrome remission compared to a control group.

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