High-Flavanol Cocoa Before a 2-Hour Sit May Reduce Backward Carotid Flow in Older Adults, Without Preventing Forward-Flow Drops

High-Flavanol Cocoa Before a 2-Hour Sit May Reduce Backward Carotid Flow in Older Adults, Without Preventing Forward-Flow Drops

Written by Alexa Heathorn, MS, CNS-c, Science Writer. In two acute randomized, double-blind, placebo-controlled crossover studies, drinking a high-flavanol cocoa immediately before a 2-hour uninterrupted sit did not prevent the sitting-related drop in forward, brain-directed carotid blood flow in young or older adults, but in older adults it appeared to blunt the usual rise in backward (retrograde) flow compared with a low-flavanol control (trend-level effect).

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Clinical Indications of Vitamin D, B12, and Folate Deficiency among Individuals with Mental Illness

Written by Chrystal Moulton, Staff Writer. Multi-regression analysis showed that vitamin D deficient schizophrenic patients were more likely to experience agoraphobia (P <0.001), higher depressive symptoms (P = 0.018), lower employment rates (P = 0.009), and worsening Global Assessment of Functioning scores (P <0.001).

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Comparative Effects of Valerian Root and Diazepam on Sleep Quality in Adults with Insomnia

Written by Keely Puchalski, ND. Results from this study demonstrated that a 100 mg dose of Valeriana officinalis extract significantly improved sleep quality in adults with self-reported insomnia. Though effects were modest, improvements in several parameters were comparable or superior to diazepam (5 mg), with fewer adverse effects reported in the valerian group after 28 days.

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Curcumin Improves Inflammatory Markers, Oxidative Stress, Liver Steatosis, and Metabolic Health in Adults with MASLD: Findings from a Randomized, Double-Blind, Placebo-Controlled Study

Written by Alexa Heathorn, MS, CNS-c, Science Writer. Daily supplementation of 1500 mg of curcumin for 12 months significantly improved inflammatory markers, oxidative stress, liver steatosis, and metabolic parameters in individuals with MASLD receiving metformin. 

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