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Vitamin D Supplementation Reduces Depressive Symptoms in Subjects with Major Depressive Disorder

Written by Taylor Woosley, Staff Writer. Significant findings of this systemic review and meta-analysis of 41 papers with a total of 53,235 participants show that subgroup analysis in participants with clinically relevant depressive symptoms (including subjects with MDD) yielded a moderate effect favoring vitamin D supplementation (Hedges’ g = −0.604, 95% CI −0.802 to −0.406, p < 0.001, I2 = 78.4%). 

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Fermented Blackberry (BB-1000) Supplementation Significantly Reduces Eye Wrinkles in Subjects

Written by Taylor Woosley, Staff Writer. 12-week supplementation with BB-1000 (blackberry fermented by Lactobacillus plantarum JBMI F5) at 800 mg/day reduced the degree of eye wrinkles to 0.22 ± 0.47 from baseline at 12 weeks. Furthermore, the skin wrinkle volumes of the BB-1000 group increased by 2.65 ± 1.94 mm3 at 12-weeks, compared to placebo (p < 0.05). 

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Vitamin D3 Repletion Improves Vascular Function and Reduces Full Length Osteopontin in Vitamin D Deficient African American Subjects

Written by Taylor Woosley, Staff Writer. Monthly supplementation of 100,000 IU of cholecalciferol was associated with a 2-fold increase in vitamin D levels, from 17 ± 5 ng/mL to 35 ± 7 ng/mL (p < 0.0001) after 12 weeks. Serum levels of log transformed flOPN were significantly reduced (p=0.03) and log FGF-23 was increased in the treated group (p = 0.04).

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Selenium Supplementation Improves Glutathione Peroxidase Activity in Alzheimer’s Patients

Written by Taylor Woosley, Staff Writer. Analysis of a systemic review of 11 studies and a meta-analysis including 6 papers show that selenium supplementation increased MDA levels significantly by an average of 0.95 (0.44, 1.45) times (p = 0.0002). Furthermore, Se only supplementation significantly increased GPX activity by an average of 0.95 (0.59, 1.31) times (p = 0.00001). 

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Omija (Schisandra chinensis) Extract and Soybean Mixture Improves Glycemic Control in Hyperglycemic Subjects

Written by Taylor Woosley, Staff Writer. 12-week supplementation of an Omija extract and soybean mixture capsule resulted in significant improvement in plasma glucose levels compared to baseline (p=0.002, 0.023, 0.041). Furthermore, OSM subjects experienced lower insulin levels and insulin AUC compared to placebo, even after adjustment of the baseline (p=0.006, 0.011). 

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Higher Dietary Niacin Consumption Decreases Migraine Risk

Written by Taylor Woosley, Staff Writer. Results of the large cross-sectional study show that compared to individuals with lower niacin consumption Q1 (12.3 mg/day), the adjusted OR values for dietary niacin intake and migraine in Q3 (18.4-26.2 mg/day) and Q4 (26.3 mg/day) were 0.78 (95%CI: 0.66-0.92, p=0.004) and 0.74 (95%CI: 0.60-0.92, p=0.009), respectively. 

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