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Quercetin Glycosides Improve Reaction Time, Preserve Cerebral Blood Flow, and Enhance Mental Vitality in Older Adults: Findings from a Randomized, Double-Blind, Placebo-Controlled Study

Written by Alexa Heathorn, MS, CNS-c, Science Writer. Daily intake of 110 mg of quercetin glycosides for 40 weeks improved reaction time and preserved brain blood flow in older adults, suggesting quercetin may help support healthy cognitive aging.

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The Hypoglycaemic Effects of the New Zealand Pine Bark Extract on Sucrose Uptake and Glycaemic Responses in Healthy Adults

Written by Keely Puchalski, ND. Results from this study demonstrated that a single 400 mg dose of New Zealand pine bark extract (Enzogenol®) significantly reduced postprandial blood glucose levels in healthy adults after a 75 g sucrose challenge. Though effects were modest, reductions in blood glucose and area under the curve (iAUC) were significant compared to placebo at 90 and 120 minutes, suggesting improved glycemic responses. The 50 mg dose showed a minor but significant reduction in peak blood glucose compared to control, and no adverse events were reported in either group.

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Low-Dose High-Phenolic Extra Virgin Olive Oil Improves Lipid Profiles in Patients with Hyperlipidemia

Written by Alexa Heathorn, MS, CNS-c, Science Writer. Daily supplementation of high-phenolic extra virgin olive oil (8 g/day, 1021 mg/kg phenols) for 4 weeks improved lipid profiles in patients with hyperlipidemia, leading to reductions in total cholesterol and lipoprotein(a) and increases in HDL cholesterol compared with lower-phenolic olive oil at higher doses.

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Nigella sativa Shows Cardioprotection in Type 1 Diabetic Children

Written by Jessica Patella, ND. Nigella sativa seed oil was shown to be safe and beneficial in pediatric patients with type 1 diabetes.  It was shown to improve cholesterol levels, LDL cholesterol, inflammatory markers and subclinical left ventricular dysfunction, suggesting a cardioprotective effect in these patients. 

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Low-Dose Ginger Extract Reduces Joint Pain, Improves Functional Capacity, and Lowers Inflammatory Markers in Adults with Mild to Moderate Joint Pain

Written by Alexa Heathorn, MS, CNS-c, Science Writer. Daily supplementation of 125 mg of ginger extract for 8 weeks reduced joint pain and stiffness, improved functional capacity, and lowered markers of inflammation in adults with mild to moderate joint pain.

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Root Causes and Brain Health: A Functional Medicine Approach to Neuro-Autoimmune Disorders with Dr. LeeAnn Steinfeldt-Manoni

Neurological autoimmune conditions – like multiple sclerosis – are notoriously complex, often leaving patients navigating vague symptoms, delayed diagnoses, and fragmented care. In this interview with Dr. LeeAnn Steinfeldt-Manoni, we discuss how functional medicine is reshaping care for neuro-autoimmune conditions…

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High-Flavanol Cocoa Before a 2-Hour Sit May Reduce Backward Carotid Flow in Older Adults, Without Preventing Forward-Flow Drops

Written by Alexa Heathorn, MS, CNS-c, Science Writer. In two acute randomized, double-blind, placebo-controlled crossover studies, drinking a high-flavanol cocoa immediately before a 2-hour uninterrupted sit did not prevent the sitting-related drop in forward, brain-directed carotid blood flow in young or older adults, but in older adults it appeared to blunt the usual rise in backward (retrograde) flow compared with a low-flavanol control (trend-level effect).

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